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Symptom Monitoring: Even though serious adverse events did not occur in trials, individual monitoring for headache, gastrointestinal symptoms, or unusual effects allows for early detection of tolerability issues and appropriate management adjustments

doi: 10.3389/fimmu.2017.00254 194 LaurenceATatoCMDavidsonTSKannoYChenZYaoZet al

In this line, GSTA1, GSTM1 and GSTP1 participate in conjugation of tobacco smoke metabolites with glutathione, thus enhancing their excretion in urine, while due to strong peroxidase activity they are among key components in cellular defense against free radical damage 9,32,33

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The prevalence of Respiratory Symptoms amongst Occupants of Households Affected Flooding in Guyana: The case of Cove John